Mathias Abegg
PD Dr. med. Dr. sc. nat.

Mathias Abegg

Oftalmologo e chirurgo oculista FMH, FEBO

Formazione

2010
Borsa di studio in chirurgia dello strabismo, Rotterdam Eye Hospital, Olanda

2008 - 2009
Fellowship per ricerca e clinica in neuroftalmologia presso University of British Columbia, Canada

2004 - 2007
Assistente presso le cliniche oculistiche universitarie di Zurigo e Berna

2000 - 2004
Programma internazionale di dottorato in Neuroscienze, Centro di Neuroscienze di Zurigo

1999 - 2004
Dottorato presso il Brain Research Institute di Zurigo

1993 - 1999
Laurea in medicina a Zurigo e Losanna 


Attività professionale

dal 06/2022
Co-proprietario e oftalmologo, ONOVIS studio oftalmologico, Berna

dal 2020
Cofondatore e direttore medico di machineMD(machineMD.com)

2014 - 2022
Medico in Ortottica presso la Clinica Universitaria di Oftalmologia, Inselspital, Berna 

2010 - 2014
Medico primario, Clinica universitaria di oftalmologia, Inselspital, Berna

2008 - 2009
Fellow in Neuroftalmologia, Università della British Columbia, Canada

2006 - 2007
Assistente medico, Clinica universitaria di oftalmologia, Inselspital, Berna

2004 - 2006
Assistente medico, Ospedale Universitario di Zurigo

1999 - 2004
Studente di dottorato, Istituto di scienze cognitive di Zurigo 



Qualifiche professionali/diplomi

2023
Corso di perfezionamento per la valutazione dell'idoneità alla guida, livello 2, Società Svizzera di Medicina Legale‍

2023
‍Certificato di competenza per il
laboratorio pratico, KHM CMPR CMB

2017
Professore associato, Università di Berna

2017
Focus principale in "Chirurgia oftalmica".

2014
Abilitazione, Università di Berna

2008
FMH & F.E.B.O. specialista in oftalmologia, 

2005
Dottorato (Dr. sc.nat.), Università di Zurigo
Titolo della dissertazione: "Neurotransmission in the Injured Brain".

2003
Diploma in Neurobiologia, Fisiologia e Biologia Molecolare, Università di Zurigo

2001
Dottorato in Medicina, Università di Zurigo
Titolo della dissertazione: "Strategie terapeutiche nella retinite pigmentosa: la luce alla fine del tunnel".


Lingue

Svizzero tedesco, tedesco, francese, inglese

Elenco delle pubblicazioni 

Bruegger, D, Grabe, H, Vicini, R, Lussi, D e Abegg, M Rilevamento dei difetti pupillari relativi all'aferenza utilizzando l'Eye Tracking e una cuffia VR.Transl Vis Sci Technol. 2023, accettato per la pubblicazione

Petzold, A., Fraser, C. L., Abegg, M., Alroughani, R., Alshowaeir, D., Alvarenga, R., Andris, C., Asgari, N., Barnett, Y., Battistella, R., Behbehani, R., Berger, T., Bikbov, M. M., Biotti, D., Biousse, V., Boschi, A., Brazdil, M., Brezhnev, A., Calabresi, P. A., ... Plant, G. T. (2022).Diagnosi e classificazione della neurite ottica. The Lancet. Neurology,21(12), 1120–1134. https://doi.org/10.1016/S1474-4422(22)00200-9

Pakeerathan, T., Havla, J., Schwake, C., Salmen, A., Bigi, S., Abegg, M., Brügger, D., Ferrazzini, T., Runge, A.-K., Breu, M., Kornek, B., Bsteh, G., Felipe-Rucián, A., Ringelstein, M., Aktas, O., Karenfort, M., Wendel, E., Kleiter, I., Hellwig, K., ... Ayzenberg, I. (2022). Un modello caratteristico di atrofia retinica permette di differenziare il MOGAD pediatrico dalla SM dopo un singolo episodio di neurite ottica. Journal of Neurology, 269(12), 6366-6376. https://doi.org/10.1007/s00415-022-11256-y

Schmid, R. D., Remlinger, J., Abegg, M., Hoepner, R., Hoffmann, R., Lukas, C., Saft, C., & Salmen, A. (2022). Nessuna alterazione della tomografia a coerenza ottica nei portatori di mutazioni della malattia di Huntington premanifesta, lontano dall'insorgenza della malattia. Brain and Behavior, 12(6), e2592. https://doi.org/10.1002/brb3.2592

Morrison, M., Kerkeni, H., Korda, A., Räss, S., Caversaccio, M. D., Abegg, M., Schneider, E., & Mantokoudis, G. (2022). Test automatico di copertura alternata per la valutazione "HINTS": uno studio di validazione. European Archives ofOto-Rhino-Laryngology: rivista ufficiale della Federazione Europea delle Società Oto-Rino-Laringologiche (EUFOS): Affiliata alla GermanSociety for Oto-Rhino-Laryngology - Head and Neck Surgery, 279(6),2873-2879. https://doi.org/10.1007/s00405-021-06998-w

Remlinger, J., Madarasz, A., Guse, K., Hoepner, R., Bagnoud, M., Meli, I., Feil, M., Abegg, M., Linington, C., Shock, A., Boroojerdi, B., Kiessling, P., Smith, B., Enzmann, V., Chan, A., & Salmen, A. (2022). Il trattamento con anticorpi antirecettore Fc antineonatale migliora l'encefalomielite sperimentale autoimmune associata a MOG-IgG. Neurology(R) Neuroimmunology &Neuroinflammation, 9(2), e1134. https://doi.org/10.1212/NXI.0000000000001134

Brueggemann, A., Bicvic, A., Goeldlin, M., Kalla, R., Kerkeni, H., Mantokoudis, G., Abegg, M., Kolníková, M., Mohaupt, M., & Bremova-Ertl, T.(2022). Effetti dell'acetil-DL-leucina sull'atassia e sul tristagmo in sei pazienti affetti da atassia teleangectasia. Journal of Child Neurology, 37(1),20-27. https://doi.org/10.1177/08830738211028394

Runge, A.-K., Remlinger, J., Abegg, M., Ferrazzini, T., Brügger, D., Weigt-Usinger, K., Lücke, T., Gold, R., & Salmen, A. (2022). Segmentazione degli strati retinici in una coorte di bambini sani mediante coerenza ottica. PloS One, 17(11), e0276958. https://doi.org/10.1371/journal.pone.0276958

Bruegger, D., Koth, A.-L., Dysli, M., Goldblum, D., Abegg, M., Tschopp, M., & Tappeiner, C. (2022). Valutazione della tabella Reddesa, un nuovo metodo di test di desaturazione del rosso, per lo screening e la classificazione della neurite ottica nella routine clinica. Frontiers in Neurology, 13, 898064. https://doi.org/10.3389/fneur.2022.898064

Belachew, Nebiyat F., Severin Baschung, William Almiri, Ruben Encinas, Johannes Kaesmacher, Tomas Dobrocky, Christoph J. Schankin, et al. (2021) Casper Versus Precise Stent for the Treatment of Patients with Idiopathic Intracranial Hypertension. Clinical Neuroradiology, May 18, 2021. https://doi.org/10.1007/s00062-021-01024-2.

Morrison, Miranda, Hassen Kerkeni, Athanasia Korda, Simone Räss, Marco D. Caversaccio, Mathias Abegg, Erich Schneider e Georgios Mantokoudis. (2021) Automated Alternate Cover Test for ‘HINTS’ Assessment: A Validation Study. European Archives of Oto-Rhino-Laryngology, July 23, 2021. https://doi.org/10.1007/s00405-021-06998-w.

Petroulia, Valentina Daphne, Dominik Brügger, Robert Hoepner, Rino Vicini, Anna Winklehner, Mathias Abegg e Franca Wagner. (2021) MRI Signs Helpful in the Differentiation of Patients with Anterior Ischaemic Optic Neuropathy and Optic Neuritis. The British Journal of Ophthalmology, July 19, 2021. https://doi.org/10.1136/bjophthalmol-2021-319537.

Bruegger, D. & M. Abegg. (2021) Prediction of Cortical Theta Oscillations in Humans for Phase-Locked Visual Stimulation. Journal of Neuroscience Methods 361 (September 1, 2021): 109288. https://doi.org/10.1016/j.jneumeth.2021.109288.

Kucur, Şerife Seda, Sebastian Häckel, Jan Stapelfeldt, Jeannine Odermatt, Milko E. Iliev, Mathias Abegg, Raphael Sznitman & Rene Höhn. (2020) Comparative Study Between the SORS and Dynamic Strategy Visual Field Testing Methods on Glaucomatous and Healthy Subjects. Translational Vision Science & Technology 9, no. 13 (December 2, 2020). https://doi.org/10.1167/tvst.9.13.3.

Veselaj, Krenar, Nicole Kamber, Myriam Briner, Christoph Friedli, Lara Diem, Kirsten Guse, Andrei Miclea, et al. (2020) Evaluation of Diagnostic Criteria and Red Flags of Myelin Oligodendrocyte Glycoprotein Encephalomyelitis in a Clinical Routine Cohort. CNS Neuroscience & Therapeutics, 13 ottobre 2020. https://doi.org/10.1111/cns.13461.

Kucur, Şerife Seda, Pablo Márquez-Neila, Mathias Abegg e Raphael Sznitman. (2019) Patient-Attentive Sequential Strategy for Perimetry-Based Visual Field Acquisition. Medical Image Analysis 54: 179–92. 

Mühlemann, Fabian, Hilary Grabe, Anthony Fok, Franca Wagner, Dominik Brügger, Claire A. Sheldon e Mathias Abegg. (2020) Homonymous Hemiatrophy of Ganglion Cell Layer from Retrochiasmal Lesions in the Visual Pathway. Neurology 94, no. 3 (21 2020): e323–29. 

Vicini, Rino, Dominik Brügger, Mathias Abegg, Anke Salmen e Hilary Michelle Grabe. (2020) Differences in Morphology and Visual Function of Myelin Oligodendrocyte Glycoprotein Antibody and Multiple Sclerosis Associated Optic Neuritis.” Journal of Neurology. 

Abegg M, Ebneter A & Dysli M. Risposta. (2019) Retina (Philadelphia, Pa.) 

Dysli M, Ebneter A, Menke M, Zinkernagel M, Wolf S, Grabe H & Abegg M. (2018) Patients with Epiretinal Membrane Display Retrograde Maculopathy after Surgical Peeling of the Internal Limiting MembraneRetina (Philadelphia, Pa.) 

Feil M, Abegg Meinrad e Abegg Mathias. (2018) Timing of Concurrent Visual Stimuli Determines Modulation of Saccadic Amplitude. Journal of Vision 18, 11:8.

Mekabaty A, Gralla J, Meier N, Abegg M, Raabe A & Mordasini P. Sinus-Stenting. (2018) Der Idiopathischen Intrakraniellen Hypertension. Schweizerisches Medizin Forum 18, no. 1 (2018): 26–28.

Borruat F, Dysli M, Voide N & Abegg M (2018). Acetazolamide Reduces Retinal Inner Nuclear Layer Thickness in Microcystic Macular Edema Secondary to Optic Neuropathy. European Neurology, 150–53. 

Feil M, Moser B & Abegg M. (2017)The Interaction of Pupil Response with the Vergence System. Graefe’s Archive for Clinical and Experimental Ophthalmology.

Brazerol J, Iliev ME, Höhn R, Fränkl S, Grabe H, Abegg M.(2017) Retrograde Maculopathy in Patients With Glaucoma. J Glaucoma. Feb 6. [Epub ahead of print]

Christen M & Abegg M. (2017) The effect of magnification and contrast on reading performance in different types of simulated low vision. Journal of Eye Movement Research, [S.l.], v. 10, n. 2.

Dysli M. & Abegg M. (2016) Nystagmus is not Limiting Reading Ability in Albinism PlosOne. Jul 8;11(7):e0158815.

Bolognini R, Gerth-Kahlert C, Abegg M, Bartholdi D, Mathis N, Sturm V, Gallati S & Schaller A. (2017) Characterization of Two Novel Intronic OPA1 Mutations Resulting in Aberrant Pre-MRNA Splicing. BMC Medical Genetics 18, no. 1 (28 2017): 22.

Abegg M. & Gentile E. (2016) Visual training in children. Therapeutische Umschau 73(2):73-7.

Ebneter A., Jaggi D., Abegg M., Wolf S. & Zinkernagel M. (2016)Relationship between presumptive inner nuclear layer thickness and geographic atrophy progression in age-related macular degeneration Invest Ophthalmol Vis Sci. Jul 1;57(9):OCT 299-306.

Dysli M. & Abegg M. (2016) 

Bär S., Hauf M., Barton JJS, Abegg M. (2015)The neural network of saccadic foreknowledge. Experimental Brain Research. 

Häner NU., Dysli M., Abegg M., Zinkernagel MS. (2015) 

Dysli M., Keller F., Abegg M. (2015) 

Abegg M., Pianezzi D., Barton JJS. (2015) A Vertical Asymmetry in Saccades. Journal of Eye Movement Research. 2015;8(5):1-10.

Dysli M., Vogel N., Abegg M. (2014) Reading performance is not affected by a prism induced increase of horizontal and vertical vergence demand. Frontiers in Human Neuroscience, 2014,8. 

Abegg M., Zinkernagel M., Wolf S. Re, Rönnbäck et al. (2014) Imaging of the macula indicates early completion of structural deficit in autosomal-dominant optic atrophy (Ophthalmology 2013;120:2672-7). Oftalmologia. 2014;121(6):e29-e30.

Dysli C., Quellec G., Abegg M., et al. (2014) Quantitative analysis of fluorescence lifetime measurements of the macula using the fluorescence lifetime imaging ophthalmoscope in healthy subjects. Invest Ophthalmol Vis Sci. 2014;55(4):2106-2113.

Abegg M., Dysli M., Wolf S., Kowal J., Dufour P., Zinkernagel M. (2014) Microcystic macular edema: retrograde maculopathy caused by optic neuropathy. Ophthalmology. 2014;121(1):142-149. doi:10.1016/j.ophtha.2013.08.045.

Abegg M., Zinkernagel M., Wolf S. (2012) Microcystic macular degeneration from optic neuropathy. Brain. 2012;135(Pt 12):e225.

Rastgardani T., Lau V., Barton JJS., Abegg M. (2012) Trial history biases the spatial programming of antisaccades. Exp Brain Res. 2012;222(3):175-183.

Sheldon CA., Abegg M., Sekunova A., Barton JJS. (2012) 

Egli M., Goldblum D., Kipfer A., et al. (2012) Assessment of a new Goldmann applanation tonometer. Br J Ophthalmol. 2012;96(1):42-46.

Abegg M., Sharma N., Barton JJS. (2012) Antisaccades generate two types of saccadic inhibition. Biol Psychol. 2012;89(1):191-194. 

Simpson SA., Abegg M., Barton JJS. (2011) Rapid adaptation of visual search in simulated hemianopia. Cereb Cortex. 2011;21(7):1593-1601.

Pfeffer G., Abegg M., Vertinsky AT., Ceccherini I., Caroli F., Barton JJS. (2011) The ocular motor features of adult-onset alexander disease: a case and review of the literature. J Neuroophthalmol. 2011;31(2):155-159.

Scheel M., Abegg M., Lanyon LJ., Mattman A., Barton JJ. (2011) White and gray matter alterations in adults with Niemann-Pick disease type C: a cross-sectional study. Neurology. 2011;76(2):201; author reply 201-202.

Abegg M, Manoach DS, Barton JJS. (2011) Knowing the future: partial foreknowledge effects on the programming of prosaccades and antisaccades. Vision Res. 2011;51(1):215-221.

Van der Stigchel S, Nijboer TCW, Bergsma DP, Abegg M, Barton JJS. (2010) Anomalous global effects induced by “blind” distractors in visual hemifield defects. Brain Cogn. 2010;74(1):66-73.

Abegg M, Rodriguez AR, Lee H, Barton JJS. (2010) "Alternate-goal bias” in antisaccades and the influence of expectation. Exp Brain Res. 2010;203(3):553-562.

Mitra AR, Abegg M, Viswanathan J, Barton JJS. (2010) Line bisection in simulated homonymous hemianopia. Neuropsychologia. 2010;48(6):1742-1749. 

Scheel M, Abegg M, Lanyon LJ, Mattman A, Barton JJ. (2010) Eye movement and diffusion tensor imaging analysis of treatment effects in a Niemann-Pick Type C patient. Mol Genet Metab. 2010;99(3):291-295.

Lee H, Abegg M, Rodriguez A, Koehn J, Barton JJS. (2010) Why do humans make antisaccade errors? Exp Brain Res. 2010;201(1):65-73. 

Abegg M, Lee H, Barton JJ. (2010) Systematic diagonal and vertical errors in antisaccades and memory-guided saccades. 2010. Journal of Eye Movement Research 2010 3,(3):5,1-10

Hugel S, Abegg M, de Paola V, Caroni P, Gähwiler BH, McKinney RA. (2009) Dendritic spine morphology determines membrane-associated protein exchange between dendritic shafts and spine heads. Cereb Cortex. 2009;19(3):697-702.

Tappeiner C, Sarra G-M, Abegg M. (2009) Abuse of vasoconstrictive eyedrops mimicking an ocular pemphigoid. Eur J Ophthalmol. 2009;19(1):129-132.

Abegg M, Fleischhauer J, Landau K. (2008) Unilateral papilledema after trabeculectomy in a patient with intracranial hypertension. Klin Monbl Augenheilkd. 2008;225(5):441-442.

Tappeiner C, Barthelmes D, Abegg MH, Wolf S, Fleischhauer JC. (2008) Impact of optic media opacities and image compression on quantitative analysis of optical coherence tomography. Invest Ophthalmol Vis Sci. 2008;49(4):1609-1614

Abegg M, Tappeiner C, Wolf-Schnurrbusch U, Barthelmes D, Wolf S, Fleischhauer J. (2008) Treatment of branch retinal vein occlusion induced macular edema with bevacizumab. BMC Ophthalmol. 2008;8:18.

Abegg MH. (2007) Rhythmic synaptic activity induced by mechanical injury of rat CA3 hippocampal area. J Neurotrauma. 2007;24(9):1536-1542.

Fischer MD, Fleischhauer J, Keusch G, Abegg MH. (2007) Rise in intraocular pressure during haemodialysis in a patient with reduced outflow facility. Br J Ophthalmol. 2007;91(8):1091-1093.

Abegg M, Kurz-Levin M, Helbig H. (2007) Retinal detachment in patients with acute retinal necrosis: a case series. Klin Monbl Augenheilkd. 2007;224(4):360-363.

Mori M, Abegg MH, Gähwiler BH, Gerber U. (2004) A frequency-dependent switch from inhibition to excitation in a hippocampal unitary circuit. Nature. 2004;431(7007):453-456

Abegg MH, Savic N, Ehrengruber MU, McKinney RA, Gähwiler BH. (2004) Epileptiform activity in rat hippocampus strengthens excitatory synapses. J Physiol (Lond). 2004;554(Pt 2):439-448.

Schwyzer L, Mateos JM, Abegg M, et al. (2002) Physiological and morphological plasticity induced by chronic treatment with NT-3 or NT-4/5 in hippocampal slice cultures. Eur J Neurosci. 2002;16(10):1939-1948.

Abegg M, Hafezi F, Wenzel A, Grimm C, Remé CE. (2000) [Therapeutic strategies in RP (retinitis pigmentosa): light at the end of the tunnel?]. Klin Monbl Augenheilkd. 2000;216(2):83-89.

Hafezi F, Grimm C, Wenzel A, Abegg M, Yaniv M, Remé CE. (1999) Retinal photoreceptors are apoptosis-competent in the absence of JunD/AP-1. Cell Death Differ. 1999;6(10):934-936.

Hafezi F, Abegg M, Grimm C, et al. (1998) Retinal degeneration in the rd mouse in the absence of c-fos. Invest Ophthalmol Vis Sci. 1998;39(12):2239-2244.



Book chapter

Abegg M. (2015) Retrograde Maculopathy. In: Optical Coherence Tomography in Multiple Sclerosis (S.151-159). Springer.

Hafezi F, Abegg M, Remé Ch.E (1998) Lichtschäden im Auge. Ein Überblick. edited by: C.Erb/ J.Flammer Risikofaktoren für Augenerkrankungen. Verlag Hans Huber.

Abegg M & Barton J. (1998) Visual Dysfunction From Lesions of the Cerebral Cortex Book chapter for Duane's Ophthalmology, Lippincott Williams & Wilkins.

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